Well, Who Do You Know? AI-powered startup Fortell has become a secret handshake for the privileged hearing-impaired crowd who swear by the product. Now, it wants to be in your ears. A secret is percolating at dinner parties, salons, and cocktail gatherings among the august New York City elite. It's whispered in the circles of financial masters of the universe, Hollywood stars, and owners of sports teams. Many haven't--or if they did hear, they might not have made out the words through noisy cross-conversations. Once they do know--particularly if they're boomers--they want it desperately. Fortell is a hearing aid, one that claims to use AI to provide a dramatically superior aural experience. The chosen few included in its beta test claim that it seems to top the performance of high-end devices they'd been unhappily using. These testers have made pilgrimages to Fortell's headquarters on the fifth floor of a WeWork facility in New York City's trendy SoHo neighborhood, where they were fitted for the hearing aids--which from the outside look pretty much like standard, over-the-ear, teardrop-shaped devices. But the big moment comes when a Fortell staffer takes them down to street level.

Scientists discover potential hearing loss reversal using arginine and Viagra for genetic mutations. New research offers hope for inherited deafness.

Cochlear implants (CI) significantly improve spoken language in children with severe-to-profound sensorineural hearing loss (SNHL), yet outcomes remain more variable than in children with normal hearing. This variability cannot be reliably predicted for individual children using age at implantation or residual hearing. This study aims to compare the accuracy of traditional machine learning (ML) to deep transfer learning (DTL) algorithms to predict post-CI spoken language development of children with bilateral SNHL using a binary classification model of high versus low language improvers. A total of 278 implanted children enrolled from three centers. The accuracy, sensitivity and specificity of prediction models based upon brain neuroanatomic features using traditional ML and DTL learning. DTL prediction models using bilinear attention-based fusion strategy achieved: accuracy of 92.39% (95% CI, 90.70%-94.07%), sensitivity of 91.22% (95% CI, 89.98%-92.47%), specificity of 93.56% (95% CI, 90.91%-96.21%), and area under the curve (AUC) of 0.977 (95% CI, 0.969-0.986). DTL outperformed traditional ML models in all outcome measures. DTL was significantly improved by direct capture of discriminative and task-specific information that are advantages of representation learning enabled by this approach over ML. The results support the feasibility of a single DTL prediction model for language prediction of children served by CI programs worldwide.

Second, we extend the work of Gardner et al.

We consider the problem of personalizing audio to maximize user experience. Briefly, we aim to find a filter $h^*$, which applied to any music or speech, will maximize the user's satisfaction. This is a black-box optimization problem since the user's satisfaction function is unknown. Substantive work has been done on this topic where the key idea is to play audio samples to the user, each shaped by a different filter $h_i$, and query the user for their satisfaction scores $f(h_i)$. A family of ``surrogate" functions is then designed to fit these scores and the optimization method gradually refines these functions to arrive at the filter $\hat{h}^*$ that maximizes satisfaction. In certain applications, we observe that a second type of querying is possible where users can tell us the individual elements $h^*[j]$ of the optimal filter $h^*$. Consider an analogy from cooking where the goal is to cook a recipe that maximizes user satisfaction. A user can be asked to score various cooked recipes (e.g., tofu fried rice) or to score individual ingredients (say, salt, sugar, rice, chicken, etc.). Given a budget of $B$ queries, where a query can be of either type, our goal is to find the recipe that will maximize this user's satisfaction. Our proposal builds on Sparse Gaussian Process Regression (GPR) and shows how a hybrid approach can outperform any one type of querying. Our results are validated through simulations and real world experiments, where volunteers gave feedback on music/speech audio and were able to achieve high satisfaction levels. We believe this idea of hybrid querying opens new problems in black-box optimization and solutions can benefit other applications beyond audio personalization.

The Discovery Engine is a general purpose automated system for scientific discovery, which combines machine learning with state-of-the-art ML interpretability to enable rapid and robust scientific insight across diverse datasets. In this paper, we benchmark the Discovery Engine against five recent peer-reviewed scientific publications applying machine learning across medicine, materials science, social science, and environmental science. In each case, the Discovery Engine matches or exceeds prior predictive performance while also generating deeper, more actionable insights through rich interpretability artefacts. These results demonstrate its potential as a new standard for automated, interpretable scientific modelling that enables complex knowledge discovery from data.

Traditional audiometry often provides an incomplete characterization of the functional impact of hearing loss on speech understanding, particularly for supra-threshold deficits common in presbycusis. This motivates the development of more diagnostically specific speech perception tests. We introduce the Simulated Phoneme Speech Test (SimPhon Speech Test) methodology, a novel, multi-stage computational pipeline for the in silico design and validation of a phonetically balanced minimal-pair speech test. This methodology leverages a modern Automatic Speech Recognition (ASR) system as a proxy for a human listener to simulate the perceptual effects of sensorineural hearing loss. By processing speech stimuli under controlled acoustic degradation, we first identify the most common phoneme confusion patterns. These patterns then guide the data-driven curation of a large set of candidate word pairs derived from a comprehensive linguistic corpus. Subsequent phases involving simulated diagnostic testing, expert human curation, and a final, targeted sensitivity analysis systematically reduce the candidates to a final, optimized set of 25 pairs (the SimPhon Speech Test-25). A key finding is that the diagnostic performance of the SimPhon Speech Test-25 test items shows no significant correlation with predictions from the standard Speech Intelligibility Index (SII), suggesting the SimPhon Speech Test captures perceptual deficits beyond simple audibility. This computationally optimized test set offers a significant increase in efficiency for audiological test development, ready for initial human trials.

Traditional audiometry often fails to fully characterize the functional impact of hearing loss on speech understanding, particularly supra-threshold deficits and frequency-specific perception challenges in conditions like presbycusis. This paper presents the development and simulated evaluation of a novel Automatic Speech Recognition (ASR)-based frequency-specific speech test designed to provide granular diagnostic insights. Our approach leverages ASR to simulate the perceptual effects of moderate sloping hearing loss by processing speech stimuli under controlled acoustic degradation and subsequently analyzing phoneme-level confusion patterns. Key findings indicate that simulated hearing loss introduces specific phoneme confusions, predominantly affecting high-frequency consonants (e.g., alveolar/palatal to labiodental substitutions) and leading to significant phoneme deletions, consistent with the acoustic cues degraded in presbycusis. A test battery curated from these ASR-derived confusions demonstrated diagnostic value, effectively differentiating between simulated normal-hearing and hearing-impaired listeners in a comprehensive simulation. This ASR-driven methodology offers a promising avenue for developing objective, granular, and frequency-specific hearing assessment tools that complement traditional audiometry. Future work will focus on validating these findings with human participants and exploring the integration of advanced AI models for enhanced diagnostic precision.

Musical (MSS) source separation of western popular music using non-causal deep learning can be very effective. In contrast, MSS for classical music is an unsolved problem. Classical ensembles are harder to separate than popular music because of issues such as the inherent greater variation in the music; the sparsity of recordings with ground truth for supervised training; and greater ambiguity between instruments. The Cadenza project has been exploring MSS for classical music. This is being done so music can be remixed to improve listening experiences for people with hearing loss. To enable the work, a new database of synthesized woodwind ensembles was created to overcome instrumental imbalances in the EnsembleSet. For the MSS, a set of ConvTasNet models was used with each model being trained to extract a string or woodwind instrument. ConvTasNet was chosen because it enabled both causal and non-causal approaches to be tested. Non-causal approaches have dominated MSS work and are useful for recorded music, but for live music or processing on hearing aids, causal signal processing is needed. The MSS performance was evaluated on the two small datasets (Bach10 and URMP) of real instrument recordings where the ground-truth is available. The performances of the causal and non-causal systems were similar. Comparing the average Signal-to-Distortion (SDR) of the synthesized validation set (6.2 dB causal; 6.9 non-causal), to the real recorded evaluation set (0.3 dB causal, 0.4 dB non-causal), shows that mismatch between synthesized and recorded data is a problem. Future work needs to either gather more real recordings that can be used for training, or to improve the realism and diversity of the synthesized recordings to reduce the mismatch...

A little over thirty years ago, when he was in his mid-forties, my friend David Howorth lost all hearing in his left ear, a calamity known as single-sided deafness. "It happened literally overnight," he said. "My doctor told me, 'We really don't understand why.' " At the time, he was working as a litigator in the Portland, Oregon, office of a large law firm. His hearing loss had no impact on his job--"In a courtroom, you can get along fine with one ear"--but other parts of his life were upended. The brain pinpoints sound sources in part by analyzing minute differences between left-ear and right-ear arrival times, the same process that helps bats and owls find prey they can't see.